The Hotel Acropoli is located near the Basilica of Santa Maria Maggiore. Guests will find many attractions within 2 kilometers of the hotel, including the famed Trevi Fountain. The Spanish Steps, the Coliseum, and Via Condotti are also within easy reach. The Hotel Acropoli is located 2 minutes' walk from the nearest public bus station or metro station. Both transit methods, along with taxis and rental cars, offer easy access to attractions as well as the international airport, which is located only 20 kilometers away from the hotel.

All of the guestrooms at the Hotel Acropoli are well appointed. All 63 rooms offer Internet access as well as climate controls. En suite bathrooms are also offered in every guestroom.

Shopping and dining selections are plentiful near the hotel. Guests will find that there is a tour desk onsite, as well as a bar. The hotel also offers an onsite dining room, an airport shuttle service, and a 24 hour Internet point.